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Mark A. Ditzler
Mark A. Ditzler
Research Scientist, NASA Ames Research Center
Verified email at nasa.gov - Homepage
Title
Cited by
Cited by
Year
Molecular dynamics and quantum mechanics of RNA: conformational and chemical change we can believe in
MA Ditzler, M Otyepka, J Sponer, NG Walter
Accounts of chemical research 43 (1), 40-47, 2010
1912010
Conformational dynamics of single pre-mRNA molecules during in vitro splicing
J Abelson, M Blanco, MA Ditzler, F Fuller, P Aravamudhan, M Wood, ...
Nature structural & molecular biology 17 (4), 504-512, 2010
1082010
A rugged free energy landscape separates multiple functional RNA folds throughout denaturation
MA Ditzler, D Rueda, J Mo, K Håkansson, NG Walter
Nucleic acids research 36 (22), 7088-7099, 2008
972008
High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase
MA Ditzler, MJ Lange, D Bose, CA Bottoms, KF Virkler, AW Sawyer, ...
Nucleic acids research 41 (3), 1873-1884, 2013
692013
Focus on function: single molecule RNA enzymology
MA Ditzler, EA Alemán, D Rueda, NG Walter
Biopolymers: Original Research on Biomolecules 87 (5‐6), 302-316, 2007
552007
Selection of 2′-deoxy-2′-fluoroarabino nucleic acid (FANA) aptamers that bind HIV-1 integrase with picomolar affinity
KM Rose, I Alves Ferreira-Bravo, M Li, R Craigie, MA Ditzler, P Holliger, ...
ACS chemical biology 14 (10), 2166-2175, 2019
532019
Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates
MA Ditzler, D Bose, N Shkriabai, B Marchand, SG Sarafianos, ...
Nucleic acids research 39 (18), 8237-8247, 2011
522011
Molecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme
MA Ditzler, J Šponer, NG Walter
Rna 15 (4), 560-575, 2009
452009
Potent inhibition of HIV-1 reverse transcriptase and replication by nonpseudoknot,“UCAA-motif” RNA aptamers
AS Whatley, MA Ditzler, MJ Lange, E Biondi, AW Sawyer, JL Chang, ...
Molecular Therapy-Nucleic Acids 2, 2013
362013
In vitro evolution of distinct self-cleaving ribozymes in diverse environments
M Popović, PS Fliss, MA Ditzler
Nucleic acids research 43 (14), 7070-7082, 2015
252015
Evolution of ribozymes in the presence of a mineral surface
JD Stephenson, M Popović, TF Bristow, MA Ditzler
RNA 22 (12), 1893-1901, 2016
152016
PURE mRNA display and cDNA display provide rapid detection of core epitope motif via high‐throughput sequencing
SG Reyes, Y Kuruma, M Fujimi, M Yamazaki, S Eto, S Nishikawa, ...
Biotechnology and bioengineering 118 (4), 1702-1715, 2021
102021
In vitro selections with RNAs of variable length converge on a robust catalytic core
M Popović, AQ Ellingson, TP Chu, C Wei, A Pohorille, MA Ditzler
Nucleic acids research 49 (2), 674-683, 2021
42021
Big on change, small on innovation: evolutionary consequences of RNA sequence duplication
A Plebanek, C Larnerd, M Popović, C Wei, A Pohorille, MA Ditzler
Journal of Molecular Evolution 87, 240-253, 2019
22019
From building blocks to cells
MA Ditzler, M Popović, T Zajkowski
New Frontiers in Astrobiology, 111-133, 2022
12022
Abzu: Uncovering the Origin of Ancient Organics on Mars
MB Wilhelm, A Ricco, D Oehler, D Buckner, A Rodriguez, P Mahaffy, ...
Bulletin of the American Astronomical Society 53 (4), 368, 2021
12021
Abzu: A Mission to Uncover the Origin of Organic Material on Mars
MB Wilhelm, AJ Ricco, DZ Oehler, G Komatsu, A Palmero Rodriguez, ...
AGU Fall Meeting Abstracts 2019, P41C-3447, 2019
12019
From Prebiotic Chemistry to Protocells: An Evolutionary Perspective II Poster
A Pohorille, MA Ditzler, M Popovic, D Lancet, M Frenkel-Pinter
2022 Astrobiology Science Conference, 2022
2022
Revealing the Possible: Synthetic Biology in the Service of Astrobiology I Oral
L Rothschild, K Adamala, A Pohorille, MA Ditzler
2022 Astrobiology Science Conference, 2022
2022
Evolution and the Origins of Life: It's all Connected
LD Williams, AS Petrov, C Alvarez, EA Smith, J Bowman, MA Ditzler
The Astrobiology Science Conference (AbSciCon) 2022, 119-01, 2022
2022
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