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Alessandro Alaimo
Alessandro Alaimo
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Calmodulin regulates the trafficking of KCNQ2 potassium channels
A Etxeberria, P Aivar, JA Rodriguez‐Alfaro, A Alaimo, P Villace, ...
The FASEB Journal 22 (4), 1135-1143, 2008
1392008
The ever changing moods of calmodulin: how structural plasticity entails transductional adaptability
A Villarroel, M Taglialatela, G Bernardo-Seisdedos, A Alaimo, J Agirre, ...
Journal of molecular biology 426 (15), 2717-2735, 2014
1022014
Calmodulin activation limits the rate of KCNQ2 K+ channel exit from the endoplasmic reticulum
A Alaimo, JC Gomez-Posada, P Aivar, A Etxeberría, JA Rodriguez-Alfaro, ...
Journal of biological chemistry 284 (31), 20668-20675, 2009
852009
Mechanosensitive piezo channels in cancer: focus on altered calcium signaling in cancer cells and in tumor progression
D De Felice, A Alaimo
Cancers 12 (7), 1780, 2020
832020
Epilepsy-causing mutations in Kv7. 2 C-terminus affect binding and functional modulation by calmodulin
P Ambrosino, A Alaimo, S Bartollino, L Manocchio, M De Maria, I Mosca, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (9 …, 2015
552015
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7. 2 potassium channels to phosphatidylinositol 4, 5-bisphosphate
MV Soldovieri, P Ambrosino, I Mosca, M De Maria, E Moretto, F Miceli, ...
Scientific reports 6 (1), 38167, 2016
452016
Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity
N Regev, N Degani-Katzav, A Korngreen, A Etzioni, S Siloni, A Alaimo, ...
PLoS One 4 (8), e6586, 2009
432009
Pivoting between calmodulin lobes triggered by calcium in the Kv7. 2/calmodulin complex
A Alaimo, A Alberdi, C Gomis-Perez, J Fernandez-Orth, ...
PLoS One 9 (1), e86711, 2014
372014
Kv7 channels can function without constitutive calmodulin tethering
JC Gomez-Posada, P Aivar, A Alberdi, A Alaimo, A Etxeberria, ...
PLoS One 6 (9), e25508, 2011
352011
Cooperativity between calmodulin-binding sites in Kv7. 2 channels
A Alaimo, A Alberdi, C Gomis-Perez, J Fernández-Orth, ...
Journal of Cell Science 126 (1), 244-253, 2013
342013
Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly destabilizing epileptogenic mutation
A Alberdi, C Gomis-Perez, G Bernardo-Seisdedos, A Alaimo, C Malo, ...
Journal of cell science 128 (21), 4014-4023, 2015
332015
The organoid era permits the development of new applications to study glioblastoma
F Andreatta, G Beccaceci, N Fortuna, M Celotti, D De Felice, M Lorenzoni, ...
Cancers 12 (11), 3303, 2020
292020
The pivotal role of TRP channels in homeostasis and diseases throughout the gastrointestinal tract
A Alaimo, J Rubert
International Journal of Molecular Sciences 20 (21), 5277, 2019
232019
An unconventional calmodulin-anchoring site within the AB module of Kv7. 2 channels
C Gomis-Perez, A Alaimo, J Fernandez-Orth, A Alberdi, P Aivar-Mateo, ...
Journal of cell science 128 (16), 3155-3163, 2015
232015
The use of dansyl-calmodulin to study interactions with channels and other proteins
A Alaimo, C Malo, P Areso, K Aloria, O Millet, A Villarroel
Ion Channels: Methods and Protocols, 217-231, 2013
222013
Surface expression and subunit specific control of steady protein levels by the Kv7. 2 helix AB linker
P Aivar, J Fernandez-Orth, C Gomis-Perez, A Alberdi, A Alaimo, ...
PLoS One 7 (10), e47263, 2012
222012
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors
A Alaimo, M Lorenzoni, P Ambrosino, A Bertossi, A Bisio, A Macchia, ...
Cell death & disease 11 (12), 1039, 2020
212020
Calmodulin: a multitasking protein in Kv7. 2 potassium channel functions
A Alaimo, A Villarroel
Biomolecules 8 (3), 57, 2018
212018
TRPM8 protein expression in hormone naïve local and lymph node metastatic prostate cancer
A Lunardi, M Barbareschi, FG Carbone, L Morelli, M Brunelli, N Fortuna, ...
Pathologica 113 (2), 95, 2021
122021
Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7. 2 channels
A Alaimo, E Nuñez, P Aivar, J Fernández-Orth, C Gomis-Perez, ...
Scientific Reports 7 (1), 13425, 2017
122017
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