Mohamed S. Abdel-Hakeem
Mohamed S. Abdel-Hakeem
University of Pennsylvania (UPenn), Cairo University (Alumni: Université de Montréal)
Verified email at
Cited by
Cited by
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
LM McLane, MS Abdel-Hakeem, EJ Wherry
Annual Review of Immunology 37, 2019
Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8+ Memory T Cells
G Badr, N Bédard, MS Abdel-Hakeem, L Trautmann, B Willems, ...
Journal of virology 82 (20), 10017-10031, 2008
Developmental relationships of four exhausted CD8+ T cell subsets reveals underlying transcriptional and epigenetic landscape control mechanisms
JC Beltra, S Manne, MS Abdel-Hakeem, M Kurachi, JR Giles, Z Chen, ...
Immunity 52 (5), 825-841. e8, 2020
Protective immunity against hepatitis C: many shades of gray
MS Abdel-Hakeem, NH Shoukry
Frontiers in immunology 5, 274, 2014
Comparison of immune restoration in early versus late alpha interferon therapy against hepatitis C virus
MS Abdel-Hakeem, N Bédard, G Badr, M Ostrowski, RP Sékaly, ...
Journal of virology 84 (19), 10429-10435, 2010
Signatures of protective memory immune responses during hepatitis C virus reinfection
MS Abdel-Hakeem, N Bédard, D Murphy, J Bruneau, NH Shoukry
Gastroenterology 147 (4), 870-881. e8, 2014
HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses.
YW Zhang, M El-Far, FP Dupuy, MS Abdel-Hakeem, Z He, FA Procopio, ...
Scientific Reports 6, 2016
Selective expansion of high functional avidity memory CD8 T cell clonotypes during hepatitis C virus reinfection and clearance
MS Abdel Hakeem, M Boisvert, J Bruneau, H Soudeyns, NH Shoukry
PLOS Pathogen 13 (2), e1006191, 2017
The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection
JJ Kotzin, F Iseka, J Wright, MB Basavappa, ML Clark, MA Ali, ...
PNAS, 2019
Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism
MA Sarhan, MS Abdel-Hakeem, AL Mason, DL Tyrrell, M Houghton
Scientific reports 7 (1), 1-12, 2017
Inhibitory signaling sustains a distinct early memory CD8+ T cell precursor that is resistant to DNA damage
JB Johnnidis, Y Muroyama, SF Ngiow, Z Chen, S Manne, Z Cai, S Song, ...
Science Immunology 6 (55), 2021
Viruses Teaching Immunology: Role of LCMV Model and Human Viral Infections in Immunological Discoveries
MS Abdel-Hakeem
Viruses 11 (2), 2019
In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
SJ Chen Z, Arai E, Khan O, Zhang Z, Ngiow SF, He Y, Huang H, Manne S, Cao Z ...
Cell 184 (5), 1262-1280, 2021
The 7th Canadian Symposium on hepatitis C virus:“Toward elimination of HCV: how to get there”
ML Cheng, MS Abdel-Hakeem, SE Cousineau, J Grebely, AD Marshall, ...
Canadian Liver Journal 1 (3), 139-152, 2018
Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19
SA Apostolidis, A Sarkar, HM Giannini, RR Goel, D Mathew, A Suzuki, ...
bioRxiv, 2021
Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation.
MS Abdel-Hakeem, S Manne, JC Beltra, E Stelekati, Z Chen, K Nzingha, ...
Nature Immunology 22, 1008-1019, 2021
The hedgehog pathway suppresses neuropathogenesis in CD4 T cell-driven inflammation
N Benallegue, H Kebir, R Kapoor, A Crockett, C Li, L Cheslow, ...
Brain, 2021
Body mass index (BMI) and alpha-fetoprotein (AFP) level correlate with the severity of HCV-induced fibrosis in a cohort of Egyptian patients with chronic HCV
AA Mohamed, AA Hemeda, RK Aziz, MS Abdel-Hakeem, M Ali-Tammam
Future Journal of Pharmaceutical Sciences 6 (1), 1-8, 2020
Expansion of Unique Hepatitis C VirusSpecific Public CD8+ T Cell Clonotypes during Acute Infection and Reinfection
S Mazouz, M Boisvert, MS Abdel-Hakeem, O Khedr, J Bruneau, ...
Journal of Immunology, 2021
A role for the transcription factor STAT5 in antagonizing CD8+ T cell exhaustion
JC Beltra, S Manne, MS Abdel-Hakeem, K Nzingha, Z Zhang, H Huang, ...
The Journal of Immunology 206 (1 Supplement), 14.13-14.13, 2021
The system can't perform the operation now. Try again later.
Articles 1–20